Strain-specific evidence reviewed. We compare Inner Health Plus, Life-Space and Ethical Nutrients — and explain what CFU counts and storage to look for.

Probiotics are live micro-organisms — mostly bacteria, but sometimes yeasts — that provide a health benefit when consumed in adequate amounts. Your gut already hosts trillions of bacteria (collectively called the gut microbiome), and probiotics are designed to add to or support that existing community.
The critical thing to understand is that not all probiotics are the same. Different strains do different things. Saying 'I take a probiotic' is a bit like saying 'I take a tablet' — the specific strain matters as much as the specific medicine. A probiotic strain that helps prevent antibiotic-associated diarrhoea may do nothing for IBS, and vice versa.
Probiotics are one of those categories where the answer really depends on the condition and the strain. The evidence is quite solid in a few specific situations, and much shakier everywhere else. These are the uses with the best support.
This is where probiotics have the strongest evidence. Antibiotics kill harmful bacteria but also wipe out beneficial gut bacteria, causing diarrhoea in roughly one in three people. Multiple high-quality studies show that taking a probiotic alongside your antibiotic course can reduce the risk of diarrhoea by around 50%. The best-studied strains for this are Saccharomyces boulardii (a beneficial yeast) and Lactobacillus rhamnosus GG. Take the probiotic at least 2 hours apart from your antibiotic dose and continue for at least one week after the course finishes.
IBS is complex and affects people differently, but several probiotic strains show moderate to strong evidence for reducing bloating, abdominal pain, and irregular bowel habits. Bifidobacterium infantis 35624 (the strain in Alflorex, available in Australia) and Lactobacillus plantarum 299v (the strain in Ethical Nutrients IBS Support) have the best clinical data. Results are modest — probiotics are not a cure for IBS — but many people report meaningful symptom improvement after 4 to 8 weeks of consistent use.
After a bout of gastro (viral or bacterial), probiotics may shorten the duration of diarrhoea by roughly one day. Lactobacillus rhamnosus GG and Saccharomyces boulardii have the most evidence here. The benefit is modest but meaningful when you are dealing with a miserable illness, particularly in children. The Gastroenterological Society of Australia notes that probiotics may be considered as an adjunct treatment for acute infectious diarrhoea.
Many probiotic products are marketed with broad health claims that go well beyond what the evidence supports. Be wary of the following claims.
Despite a lot of marketing, there is no convincing evidence that any probiotic causes meaningful weight loss in humans. Some preliminary research suggests the gut microbiome plays a role in metabolism, but we are a long way from a 'weight loss probiotic'. Any product making this claim is getting ahead of the science.
You will see 'supports immune health' on many probiotic labels. While around 70% of immune tissue does reside in the gut, the idea that taking a probiotic supplement will meaningfully boost your immune system in a clinically relevant way is not well supported. Some studies in specific populations (elderly, daycare children) show marginal reductions in upper respiratory infections, but the effects are small and inconsistent.
The 'gut-brain axis' is a legitimate area of research, and so-called 'psychobiotics' generate plenty of headlines. However, current human studies are small, short-term, and produce inconsistent results. If you are experiencing anxiety or depression, evidence-based treatments (GP consultation, psychological therapy, medication) should be the priority — not a probiotic supplement.
Some studies suggest certain strains may slightly reduce the duration of upper respiratory tract infections, but the effect size is small (roughly half a day shorter) and not all studies agree. Washing your hands and getting your flu vaccination are far more effective strategies.
If you are going to take a probiotic, match the strain to the condition. This table summarises the best-studied strains for specific uses.
| Condition | Best-Studied Strain(s) | Evidence Level |
|---|---|---|
| Antibiotic-associated diarrhoea | Saccharomyces boulardii; Lactobacillus rhamnosus GG | Strong |
| IBS (bloating, pain, irregularity) | Lactobacillus plantarum 299v; Bifidobacterium infantis 35624 | Moderate-Strong |
| Infectious diarrhoea / gastro recovery | Lactobacillus rhamnosus GG; Saccharomyces boulardii | Moderate |
| Constipation | Bifidobacterium lactis HN019; Bifidobacterium lactis BB-12 | Moderate |
| Preventing traveller's diarrhoea | Saccharomyces boulardii | Moderate |
| Eczema prevention (infants) | Lactobacillus rhamnosus GG (taken by mother during pregnancy) | Moderate |
We compared five of the most popular probiotic products available in Australian pharmacies and supermarkets. The right choice depends on what you are taking it for, not just the CFU count on the label.
| Product | Key Strains | CFU Count | Best For | Refrigeration | Form |
|---|---|---|---|---|---|
Inner Health Plus | L. acidophilus (HOWARU), B. lactis HN019 | 25 billion | General digestive health | Capsules | |
Ethical Nutrients IBS Support | L. plantarum 299v | 20 billion | IBS symptom relief | No (shelf-stable) | Capsules |
Life-Space Broad Spectrum | 15 strains including Lactobacillus & Bifidobacterium spp. | 32 billion | Strain diversity / general gut health | Capsules | |
Yakult Original | Lacticaseibacillus paracasei Shirota | 6.5 billion per bottle | Daily maintenance / kids | Yes (fridge drink) | Liquid (65mL) |
Chemist Own Probiotic 35 Billion | Multi-strain blend | 35 billion | Budget general-purpose option | Capsules |
These are widely available across Australian pharmacies. Prices vary — check your preferred retailer for current pricing.
The Australian probiotic market is crowded and confusing. Here is what to look for — and what to ignore — when choosing a product.
Probiotics are the live bacteria themselves. Prebiotics are types of dietary fibre that feed the beneficial bacteria already living in your gut. Think of it this way: probiotics are the seeds, and prebiotics are the fertiliser.
Common prebiotics include inulin, fructo-oligosaccharides (FOS), and galacto-oligosaccharides (GOS). You get them naturally from foods like onions, garlic, bananas, oats, and asparagus. Some probiotic products include added prebiotics — these are sometimes labelled 'synbiotics'.
For most people, eating a varied diet rich in plant-based fibre is the simplest and most cost-effective way to support your gut microbiome — arguably more beneficial than any supplement. The Gastroenterological Society of Australia recommends aiming for 25-30 grams of dietary fibre per day.
This is the use with the strongest evidence. If you are taking an antibiotic and want to reduce the risk of antibiotic-associated diarrhoea, look for a product containing Saccharomyces boulardii or Lactobacillus rhamnosus GG, as these strains have the best clinical data for this purpose. Saccharomyces boulardii is a particularly practical choice because, as a yeast, it is not affected by antibacterial antibiotics. Take your probiotic at least 2 to 3 hours apart from your antibiotic dose, and continue for at least one week after the course finishes. Match the strain on the label to the evidence rather than choosing on cell count alone.
There is no single 'women's probiotic' strain that suits everyone — the right choice still depends on what you want help with. Some products marketed to women add specific Lactobacillus strains aimed at vaginal and urinary health, but the evidence here is mixed and strain-specific. For general gut symptoms, the same rule applies as for everyone else: match the strain to the condition. If you are pregnant, breastfeeding, or managing a urinary or vaginal health concern, speak to your pharmacist or GP before starting a supplement so you can choose an appropriate option.
You do not necessarily need a supplement to get probiotics. Fermented foods contain live cultures and have been part of human diets for thousands of years. While the strains and amounts are less standardised than supplements, regularly eating fermented foods is associated with improved gut microbiome diversity.
There is no single product that every pharmacist or GP recommends, because the best choice depends on what you are taking it for. Inner Health Plus is one of the most commonly stocked daily probiotics in Australian pharmacies, while Ethical Nutrients IBS Support is frequently suggested for IBS symptoms because it contains a clinically trialled strain. For antibiotic-associated diarrhoea, a Saccharomyces boulardii product is a common recommendation. Rather than asking for the most popular brand, tell your pharmacist what you want help with and ask which strain has evidence for it.
The strains with the best clinical data for IBS are Lactobacillus plantarum 299v (the strain in Ethical Nutrients IBS Support, which is shelf-stable) and Bifidobacterium infantis 35624. These may help relieve IBS symptoms such as bloating, abdominal pain and irregular bowel habits, though results are modest and can take 4 to 8 weeks of consistent use. Probiotics are not a cure for IBS — if your symptoms are new, severe, or changing, see your GP first to rule out other causes.
CFU stands for colony-forming units — essentially how many live organisms are in each dose. A strain is a specific, individually identified type of bacteria or yeast, written as genus, species and a strain code (for example Lactobacillus rhamnosus GG). The clinical evidence sits at the strain level, so the strain identity matters more than a big CFU number. A product with 50 billion CFU of a well-studied strain can be a better match than one with 100 billion CFU of an unidentified strain. Choose the strain with evidence for your concern first, then check the cell count is in the studied range and guaranteed at expiry.
For bloating linked to IBS, certain strains — particularly Lactobacillus plantarum 299v and Bifidobacterium infantis 35624 — may help reduce symptoms over several weeks. The benefit is strain-specific and modest, not guaranteed. Confusingly, some people notice more gas and bloating in the first week of starting any probiotic; this is common and usually settles, but if you start a lower dose and build up it can be gentler. If bloating is persistent, painful, or comes with other red-flag symptoms, see your GP rather than relying on a supplement.
Both views can be true at once, because 'probiotics' is a huge category. The sceptical headlines usually refer to general probiotic supplements taken by healthy people for vague goals like 'immunity' or 'wellbeing', where the evidence really is weak. The supportive evidence is narrower and strain-specific: particular strains have good data for antibiotic-associated diarrhoea and for IBS symptoms. So a blanket 'probiotics don't work' overstates it, and a blanket 'probiotics fix your gut' does too. The honest answer is that some strains help with some conditions, and the rest is marketing.
Both — the evidence supports taking a probiotic during your antibiotic course and continuing for at least one week after it finishes. Space the probiotic at least 2 to 3 hours apart from each antibiotic dose so the antibiotic does not immediately knock out the probiotic organisms. Saccharomyces boulardii and Lactobacillus rhamnosus GG are the best-studied strains for reducing antibiotic-associated diarrhoea.
Probiotics are the live bacteria or yeasts themselves. Prebiotics are types of dietary fibre — such as inulin and fructo-oligosaccharides (FOS) — that feed the beneficial bacteria already living in your gut. A simple way to remember it: probiotics are the seeds, prebiotics are the fertiliser. You get prebiotics naturally from foods like onions, garlic, bananas, oats and asparagus. Products that combine both are sometimes labelled 'synbiotics'.
For most conditions, yes — consistency matters. Probiotics do not permanently colonise your gut. Once you stop taking them, the supplemented strains typically decline within 1 to 3 weeks. If you are taking a probiotic for an ongoing condition like IBS, daily use is recommended. For short-term use alongside antibiotics, take them for the duration of the antibiotic course plus at least one week after.
Yes, and this is actually one of the strongest evidence-based uses for probiotics. The key is timing: take your probiotic at least 2 to 3 hours apart from your antibiotic dose so the antibiotic does not immediately kill the probiotic organisms. Saccharomyces boulardii is a particularly good choice during antibiotic courses because, as a yeast, it is naturally resistant to antibacterial antibiotics.
Not necessarily. Price does not reliably predict quality or effectiveness. What matters is whether the product contains a clinically studied strain at an adequate dose for your condition, and whether the CFU count is guaranteed at expiry. Pharmacy own-brand probiotics (like Chemist Own) often contain comparable strains and CFU counts to premium brands at a lower price. Always compare the strain and CFU, not just the brand name.
Some probiotic strains, particularly Lactobacillus rhamnosus GG, have been studied during pregnancy and appear to be safe. Research suggests they may help reduce the risk of eczema in infants when taken during the third trimester and breastfeeding. However, you should always discuss any new supplement with your GP or pharmacist during pregnancy.
AUST L (Listed) products have been assessed by the TGA for safety and quality, and their ingredients must be from a pre-approved list. Most probiotics fall into this category. AUST R (Registered) products undergo a more rigorous evaluation for efficacy and are typically prescription medicines. An AUST L number on a probiotic confirms it meets Australian manufacturing and safety standards.
It depends on the formulation. Many traditional probiotic strains need refrigeration to stay alive and potent. Products in the pharmacy fridge are not necessarily better — they just contain strains that require cold storage. Some newer products use microencapsulation or inherently robust strains (like Saccharomyces boulardii or Lactobacillus plantarum 299v) that are shelf-stable. The key is to follow the storage instructions on the specific product you buy.
This information is general in nature and isn’t a substitute for professional medical advice. Always read the label and follow the directions for use. Talk to your pharmacist or doctor about what’s right for you.

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